THE SLC36 TRANSPORTER PATHETIC IS REQUIRED FOR NEURAL STEM CELL PROLIFERATION AND FOR BRAIN GROWTH UNDER NUTRITION RESTRICTION

The SLC36 transporter Pathetic is required for neural stem cell proliferation and for brain growth under nutrition restriction

Abstract Background Drosophila neuroblasts (NBs) are neural stem cells whose maintenance relies on Notch activity.NBs proliferate throughout larval stages to generate a large number Equestrian Helmets of adult neurons.Their proliferation is protected under conditions of nutrition restriction but the mechanisms responsible are not fully understood.A

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Dynamic SOFA score assessments to predict outcomes after acute admission of octogenarians to the intensive care unit

Background Identifying which octogenarians could benefit most from continuing critical care is challenging.We aimed to see if responses to therapies using the sequential organ failure assessment (SOFA) score on day 4 after unplanned admission to the intensive care unit (ICU) could be associated with short-term mortality.Methods In this prospective

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In-situ measurement of the meniscus at the entry and exit of grease and oil lubricated rolling bearing contacts

The lubricant inlet meniscus in a rolling element bearing acts as a reservoir that feeds the elastohydrodynamic contact, resulting in a sufficiently thick film to avoid wear.A shortening and/or thinning of the inlet meniscus towards the Sleepwear contact centre is an indicator of bearing starvation and impaired lubricant performance.This work intro

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